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Inhibitory Quotient (Cmin/?) for Amprenavir
 
Slide 17 of 22
 
Speaker notes: These data have all been published in the last few months by different authors.

Shows that IQ is calculated in different ways by different authors, so must take care when comparing IQ values.

The numbers achieved by different methods for amprenavir are relatively similar, so possibly not too much of a problem comparing these:
  • however, it is important to note that IQ for a certain drug is not a 'fixed number'; values will vary according to how and where the study is done.
Again, it is the rank order and the approximate scale of the differences in IQ between ARV drugs that is important, rather than the actual values.

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