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Do Not Coadminister

Emtricitabine/Tenofovir alafenamide (FTC/TAF)

Doravirine/Lamivudine/ Tenofovir-DF (DOR/3TC/TDF)

Quality of Evidence: Very Low

Summary:

Delstrigo (doravirine, lamivudine, tenofovir-DF) is indicated for use as a complete regimen for the treatment of HIV 1 infection and must not be administered with other antiretroviral products. Furthermore, Delstrigo contains lamivudine and tenofovir-DF and should not be administered products containing emtricitabine or tenofovir alafenamide.

Description:

Descovy should not be administered concomitantly with medicinal products containing tenofovir disoproxil or lamivudine.
Descovy Summary of Product Characteristics, Gilead Sciences Ltd, April 2022.

Doravirine/lamivudine/tenofovir disoproxil must not be co-administered with medicinal products containing tenofovir alafenamide. Delstrigo is a complete regimen for the treatment of HIV-1 infection; therefore, Delstrigo should not be administered with other antiretroviral medicinal products. 
Delstrigo Summary of Product Characteristics, Merck Sharp & Dohme Ltd, November 2018.

Because Delstrigo is a complete regimen for the treatment of HIV-1 infection, co-administration with other antiretroviral medications for treatment of HIV-1 infection is not recommended.
Delstrigo US Prescribing Information, Merck & Co Inc, August 2018.

View all available interactions with Emtricitabine/Tenofovir alafenamide (FTC/TAF) by clicking here.

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