Triumeq (dolutegravir, abacavir, lamivudine) is indicated for use as a complete regimen for the treatment of HIV-1 infection and coadministration with nevirapine is not recommended. Nevirapine, an inducer of CYP3A4, could potentially decrease dolutegravir concentrations. However, in specific clinical situations where an intensification of HIV treatment is needed, coadministration with nevirapine would be possible from a pharmacokinetic standpoint if an additional dolutegravir 50 mg tablet, separated by 12 hours from Triumeq, is taken. Note, the bioavailability of lamivudine has been shown to be significantly reduced in a dose dependent manner by sorbitol which is present in liquid formulations such as nevirapine oral suspension.