No Interaction Expected
Emtricitabine/Tenofovir-DF (FTC/TDF, PrEP)
Quality of Evidence:
Coadministration has not been studied but based on metabolism and clearance a clinically significant interaction is unlikely. Trastuzumab emtansine is a monoclonal antibody-drug conjugate. Trastuzumab does not undergo CYP mediated metabolism, whereas DM1 (an active component of emtansine) is metabolized by CYP3A4. Emtricitabine and tenofovir-DF do not interfere with trastuzumab emtansine elimination.
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Emtricitabine/Tenofovir-DF (FTC/TDF, PrEP) by clicking