No Interaction Expected
Emtricitabine/Tenofovir-DF (FTC/TDF, PrEP)
Colecalciferol (Vitamin D3) [alone]
Quality of Evidence:
Coadministration has not been studied but based on metabolism and clearance a clinically significant interaction is unlikely. Metabolism of vitamin D to active metabolites occurs in the liver and kidneys, and is thought to involve CYP3A4 and CYP24A1. There is little potential for an interaction with emtricitabine and tenofovir-DF via modulation of, or competition for, metabolic pathways.
View all available interactions with
Emtricitabine/Tenofovir-DF (FTC/TDF, PrEP) by clicking