No Interaction Expected
Emtricitabine/Tenofovir-DF (FTC/TDF, PrEP)
Retinol (Vitamin A) [alone]
Quality of Evidence:
Coadministration has not been studied but based on metabolism and clearance a clinically significant interaction is unlikely. Vitamin A esters are hydrolysed by pancreatic enzymes to retinol, which is then absorbed and re-esterified. Some retinol is stored in the liver. Retinol not stored in the liver undergoes glucuronide conjugation and subsequent oxidation to retinal and retinoic acid.
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Emtricitabine/Tenofovir-DF (FTC/TDF, PrEP) by clicking