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Do Not Coadminister

Emtricitabine/Tenofovir alafenamide (FTC/TAF)

Rilpivirine/ Emtricitabine/Tenofovir-DF (RPV/FTC/TDF)

Quality of Evidence: Very Low

Summary:

Eviplera/Complera (rilpivirine, emtricitabine, tenofovir-DF) is indicated for use as a complete regimen for the treatment of HIV-1 infection and should not be administered with other antiretroviral products. Furthermore, both products contain emtricitabine and must not be administered with other products containing emtricitabine. In addition, Eviplera/Complera contains tenofovir-DF and should not be administered with tenofovir alafenamide.

Description:

Eviplera should not be administered concomitantly with other medicinal products containing emtricitabine.
Eviplera Summary of Product Information, Gilead Sciences Ltd, August 2021.

Because Complera is a complete regimen, coadministration with other antiretroviral medications for the treatment of HIV-1 infection is not recommended.
Complera US Prescribing Information, Gilead Sciences Inc, November 2019.

Descovy should not be administered concomitantly with medicinal products containing tenofovir disoproxil or emtricitabine.
Descovy Summary of Product Characteristics, Gilead Sciences Ltd, April 2022.

View all available interactions with Emtricitabine/Tenofovir alafenamide (FTC/TAF) by clicking here.

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