Interaction Checker

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No Interaction Expected

Efavirenz (EFV)

Abacavir (ABC)

No Interaction Expected

Efavirenz (EFV)

Acamprosate

No Interaction Expected

Efavirenz (EFV)

Acarbose

Potential Interaction

Efavirenz (EFV)

Acenocoumarol

No Interaction Expected

Efavirenz (EFV)

Acetazolamide

No Interaction Expected

Efavirenz (EFV)

Aciclovir (Acyclovir)

No Interaction Expected

Efavirenz (EFV)

Acitretin

No Interaction Expected

Efavirenz (EFV)

Aclidinium bromide

No Interaction Expected

Efavirenz (EFV)

Adalimumab

No Interaction Expected

Efavirenz (EFV)

Adefovir

No Interaction Expected

Efavirenz (EFV)

Adrenaline (Epinephrine)

No Interaction Expected

Efavirenz (EFV)

African Potato

No Interaction Expected

Efavirenz (EFV)

Agomelatine

Potential Weak Interaction

Efavirenz (EFV)

Albendazole

No Interaction Expected

Efavirenz (EFV)

Albuvirtide

No Interaction Expected

Efavirenz (EFV)

Alcohol

No Interaction Expected

Efavirenz (EFV)

Alcuronium

No Interaction Expected

Efavirenz (EFV)

Alendronic Acid

Potential Interaction

Efavirenz (EFV)

Alfentanil

Potential Interaction

Efavirenz (EFV)

Alfuzosin

No Interaction Expected

Efavirenz (EFV)

Aliskiren

No Interaction Expected

Efavirenz (EFV)

Allopurinol

No Interaction Expected

Efavirenz (EFV)

Almotriptan

No Interaction Expected

Efavirenz (EFV)

Aloe vera

No Interaction Expected

Efavirenz (EFV)

Alosetron

Potential Interaction

Efavirenz (EFV)

Alprazolam

No Interaction Expected

Efavirenz (EFV)

Amantadine

No Interaction Expected

Efavirenz (EFV)

Ambrisentan

No Interaction Expected

Efavirenz (EFV)

Amikacin

No Interaction Expected

Efavirenz (EFV)

Amiloride

No Interaction Expected

Efavirenz (EFV)

Aminophylline

Potential Interaction

Efavirenz (EFV)

Amiodarone

No Interaction Expected

Efavirenz (EFV)

Amisulpride

No Interaction Expected

Efavirenz (EFV)

Amitriptyline

Potential Interaction

Efavirenz (EFV)

Amlodipine

Do Not Coadminister

Efavirenz (EFV)

Amodiaquine

No Interaction Expected

Efavirenz (EFV)

Amoxicillin

No Interaction Expected

Efavirenz (EFV)

Amphetamine

No Interaction Expected

Efavirenz (EFV)

Amphotericin B

No Interaction Expected

Efavirenz (EFV)

Ampicillin

Potential Interaction

Efavirenz (EFV)

Anastrozole

No Interaction Expected

Efavirenz (EFV)

Anidulafungin

No Interaction Expected

Efavirenz (EFV)

Antacids

No Interaction Expected

Efavirenz (EFV)

Anti-thymocyte globulin

Potential Interaction

Efavirenz (EFV)

Apixaban

Potential Weak Interaction

Efavirenz (EFV)

Apomorphine

Potential Interaction

Efavirenz (EFV)

Aprepitant

No Interaction Expected

Efavirenz (EFV)

Argatroban

Potential Interaction

Efavirenz (EFV)

Aripiprazole

Potential Interaction

Efavirenz (EFV)

Artemisinin

No Interaction Expected

Efavirenz (EFV)

Ascorbic Acid (Vitamin C) [in multivitamins]

Potential Interaction

Efavirenz (EFV)

Asenapine

No Interaction Expected

Efavirenz (EFV)

Asparaginase

No Interaction Expected

Efavirenz (EFV)

Aspirin (Analgesic)

No Interaction Expected

Efavirenz (EFV)

Aspirin (Anti-platelet)

Do Not Coadminister

Efavirenz (EFV)

Astemizole

Do Not Coadminister

Efavirenz (EFV)

Atazanavir alone (ATV)

Do Not Coadminister

Efavirenz (EFV)

Atazanavir/cobicistat (ATV/c)

Do Not Coadminister

Efavirenz (EFV)

Atazanavir + ritonavir (ATV/r)

No Interaction Expected

Efavirenz (EFV)

Atenolol

Potential Interaction

Efavirenz (EFV)

Atorvastatin

Potential Interaction

Efavirenz (EFV)

Atovaquone

No Interaction Expected

Efavirenz (EFV)

Atropine

Potential Interaction

Efavirenz (EFV)

Avanafil

No Interaction Expected

Efavirenz (EFV)

Azathioprine

No Interaction Expected

Efavirenz (EFV)

Azithromycin

No Interaction Expected

Efavirenz (EFV)

Baclofen

No Interaction Expected

Efavirenz (EFV)

Basiliximab

No Interaction Expected

Efavirenz (EFV)

Beclometasone

Potential Interaction

Efavirenz (EFV)

Bedaquiline

No Interaction Expected

Efavirenz (EFV)

Belatacept

No Interaction Expected

Efavirenz (EFV)

Benazepril

No Interaction Expected

Efavirenz (EFV)

Bendroflumethiazide

No Interaction Expected

Efavirenz (EFV)

Benserazide

No Interaction Expected

Efavirenz (EFV)

Benznidazole

Do Not Coadminister

Efavirenz (EFV)

Bepridil

No Interaction Expected

Efavirenz (EFV)

Betahistine

Potential Interaction

Efavirenz (EFV)

Betamethasone

No Interaction Expected

Efavirenz (EFV)

Betrixaban

No Interaction Expected

Efavirenz (EFV)

Bevacizumab

Potential Interaction

Efavirenz (EFV)

Bexarotene

No Interaction Expected

Efavirenz (EFV)

Bezafibrate

Do Not Coadminister

Efavirenz (EFV)

Bictegravir/ Emtricitabine/Tenofovir alafenamide (BIC/FTC/TAF)

No Interaction Expected

Efavirenz (EFV)

Biperiden

No Interaction Expected

Efavirenz (EFV)

Bisacodyl

Potential Weak Interaction

Efavirenz (EFV)

Bisoprolol

No Interaction Expected

Efavirenz (EFV)

Bleomycin

Potential Interaction

Efavirenz (EFV)

Bortezomib

Potential Interaction

Efavirenz (EFV)

Bosentan

Potential Weak Interaction

Efavirenz (EFV)

Bromazepam

Potential Interaction

Efavirenz (EFV)

Budesonide

Potential Interaction

Efavirenz (EFV)

Bupivacaine

Potential Interaction

Efavirenz (EFV)

Buprenorphine

Potential Interaction

Efavirenz (EFV)

Bupropion (Amfebutamone)

Potential Interaction

Efavirenz (EFV)

Buspirone

No Interaction Expected

Efavirenz (EFV)

Caffeine citrate

No Interaction Expected

Efavirenz (EFV)

Calcium folinate

No Interaction Expected

Efavirenz (EFV)

Calcium supplements

No Interaction Expected

Efavirenz (EFV)

Canagliflozin

No Interaction Expected

Efavirenz (EFV)

Candesartan

Potential Interaction

Efavirenz (EFV)

Cannabidiol (CBD)

Potential Interaction

Efavirenz (EFV)

Cannabis

No Interaction Expected

Efavirenz (EFV)

Capecitabine

No Interaction Expected

Efavirenz (EFV)

Capreomycin

No Interaction Expected

Efavirenz (EFV)

Captopril

Potential Interaction

Efavirenz (EFV)

Carbamazepine

No Interaction Expected

Efavirenz (EFV)

Carbidopa

No Interaction Expected

Efavirenz (EFV)

Carbimazole

No Interaction Expected

Efavirenz (EFV)

Carboplatin

Potential Weak Interaction

Efavirenz (EFV)

Carvedilol

Potential Interaction

Efavirenz (EFV)

Caspofungin

Potential Interaction

Efavirenz (EFV)

Cat's Claw (Uncaria tomentosa)

No Interaction Expected

Efavirenz (EFV)

Cefalexin

No Interaction Expected

Efavirenz (EFV)

Cefazolin

No Interaction Expected

Efavirenz (EFV)

Cefixime

No Interaction Expected

Efavirenz (EFV)

Cefotaxime

No Interaction Expected

Efavirenz (EFV)

Ceftazidime

No Interaction Expected

Efavirenz (EFV)

Ceftriaxone

Potential Interaction

Efavirenz (EFV)

Celecoxib

No Interaction Expected

Efavirenz (EFV)

Cetirizine

No Interaction Expected

Efavirenz (EFV)

Cetuximab

No Interaction Expected

Efavirenz (EFV)

Chlorambucil

Potential Weak Interaction

Efavirenz (EFV)

Chloramphenicol

Potential Interaction

Efavirenz (EFV)

Chlordiazepoxide

Potential Weak Interaction

Efavirenz (EFV)

Chloroquine

No Interaction Expected

Efavirenz (EFV)

Chlorphenamine

No Interaction Expected

Efavirenz (EFV)

Chlorpromazine

No Interaction Expected

Efavirenz (EFV)

Chlortalidone

No Interaction Expected

Efavirenz (EFV)

Ciclesonide

Potential Interaction

Efavirenz (EFV)

Ciclosporin (Cyclosporine)

No Interaction Expected

Efavirenz (EFV)

Cidofovir

No Interaction Expected

Efavirenz (EFV)

Cilazapril

No Interaction Expected

Efavirenz (EFV)

Cimetidine

No Interaction Expected

Efavirenz (EFV)

Ciprofloxacin

Do Not Coadminister

Efavirenz (EFV)

Cisapride

No Interaction Expected

Efavirenz (EFV)

Cisatracurium

No Interaction Expected

Efavirenz (EFV)

Cisplatin

Potential Weak Interaction

Efavirenz (EFV)

Citalopram

Potential Interaction

Efavirenz (EFV)

Clarithromycin

No Interaction Expected

Efavirenz (EFV)

Clavulanic acid

Potential Interaction

Efavirenz (EFV)

Clindamycin

Potential Interaction

Efavirenz (EFV)

Clobazam

No Interaction Expected

Efavirenz (EFV)

Clobetasol

No Interaction Expected

Efavirenz (EFV)

Clofazimine

No Interaction Expected

Efavirenz (EFV)

Clofibrate

No Interaction Expected

Efavirenz (EFV)

Clomifene

Potential Weak Interaction

Efavirenz (EFV)

Clomipramine (Chlorimipramine)

Potential Interaction

Efavirenz (EFV)

Clonazepam

No Interaction Expected

Efavirenz (EFV)

Clonidine

Potential Interaction

Efavirenz (EFV)

Clopidogrel

Potential Interaction

Efavirenz (EFV)

Clorazepate

No Interaction Expected

Efavirenz (EFV)

Cloxacillin

Potential Interaction

Efavirenz (EFV)

Clozapine

Potential Interaction

Efavirenz (EFV)

Cocaine

Potential Weak Interaction

Efavirenz (EFV)

Codeine

Potential Weak Interaction

Efavirenz (EFV)

Colchicine

No Interaction Expected

Efavirenz (EFV)

Colecalciferol (Vitamin D3) [in multivitamins]

No Interaction Expected

Efavirenz (EFV)

Cubeb pepper (Piper cubeba)

No Interaction Expected

Efavirenz (EFV)

Cyanocobalamin (Vitamin B12) [in multivitamins]

Potential Interaction

Efavirenz (EFV)

Cyclophosphamide

No Interaction Expected

Efavirenz (EFV)

Cycloserine

Potential Interaction

Efavirenz (EFV)

Cyproterone acetate

No Interaction Expected

Efavirenz (EFV)

Cytarabine

No Interaction Expected

Efavirenz (EFV)

Dabigatran

No Interaction Expected

Efavirenz (EFV)

Dacarbazine

Potential Interaction

Efavirenz (EFV)

Daclatasvir

No Interaction Expected

Efavirenz (EFV)

Dactinomycin

No Interaction Expected

Efavirenz (EFV)

Dalteparin

No Interaction Expected

Efavirenz (EFV)

Dapagliflozin

No Interaction Expected

Efavirenz (EFV)

Dapsone

Potential Interaction

Efavirenz (EFV)

Darifenacin

Do Not Coadminister

Efavirenz (EFV)

Darunavir/cobicistat (DRV/c)

Do Not Coadminister

Efavirenz (EFV)

Darunavir/Cobicistat/ Emtricitabine/Tenofovir alafenamide (DRV/c/FTC/TAF)

Potential Interaction

Efavirenz (EFV)

Darunavir + ritonavir (DRV/r)

Potential Interaction

Efavirenz (EFV)

Dasatinib

No Interaction Expected

Efavirenz (EFV)

Daunorubicin

Potential Weak Interaction

Efavirenz (EFV)

Delamanid

No Interaction Expected

Efavirenz (EFV)

Denosumab

No Interaction Expected

Efavirenz (EFV)

Desflurane

No Interaction Expected

Efavirenz (EFV)

Desipramine

Do Not Coadminister

Efavirenz (EFV)

Desogestrel (COC)

Do Not Coadminister

Efavirenz (EFV)

Desogestrel (POP)

Potential Interaction

Efavirenz (EFV)

Dexamethasone

Potential Weak Interaction

Efavirenz (EFV)

Dexmedetomidine

Potential Interaction

Efavirenz (EFV)

Dextropropoxyphene

Potential Interaction

Efavirenz (EFV)

Diamorphine (diacetylmorphine)

Potential Interaction

Efavirenz (EFV)

Diazepam

Potential Interaction

Efavirenz (EFV)

Diclofenac

No Interaction Expected

Efavirenz (EFV)

Didanosine (ddI)

No Interaction Expected

Efavirenz (EFV)

Diethylcarbamazine

No Interaction Expected

Efavirenz (EFV)

Digoxin

Potential Weak Interaction

Efavirenz (EFV)

Dihydrocodeine

Do Not Coadminister

Efavirenz (EFV)

Dihydroergotamine

No Interaction Expected

Efavirenz (EFV)

Diloxanide

Potential Interaction

Efavirenz (EFV)

Diltiazem

No Interaction Expected

Efavirenz (EFV)

Diphenhydramine

Potential Interaction

Efavirenz (EFV)

Dipyridamole

Potential Interaction

Efavirenz (EFV)

Disopyramide

No Interaction Expected

Efavirenz (EFV)

Disulfiram

Potential Interaction

Efavirenz (EFV)

Docetaxel

Potential Interaction

Efavirenz (EFV)

Dofetilide

No Interaction Expected

Efavirenz (EFV)

Dolasetron

Potential Interaction

Efavirenz (EFV)

Dolutegravir (DTG)

Potential Interaction

Efavirenz (EFV)

Dolutegravir/Abacavir/ Lamivudine (DTG/ABC/3TC)

Potential Interaction

Efavirenz (EFV)

Dolutegravir/Lamivudine (DTG/3TC)

Do Not Coadminister

Efavirenz (EFV)

Dolutegravir/Rilpivirine (DTG/RPV)

Potential Interaction

Efavirenz (EFV)

Domperidone

No Interaction Expected

Efavirenz (EFV)

Dopamine

Do Not Coadminister

Efavirenz (EFV)

Doravirine (DOR)

Do Not Coadminister

Efavirenz (EFV)

Doravirine/Lamivudine/ Tenofovir-DF (DOR/3TC/TDF)

Potential Interaction

Efavirenz (EFV)

Doxazosin

No Interaction Expected

Efavirenz (EFV)

Doxepin

No Interaction Expected

Efavirenz (EFV)

Doxorubicin

Potential Interaction

Efavirenz (EFV)

Doxycycline

Potential Interaction

Efavirenz (EFV)

Droloxifene

Potential Interaction

Efavirenz (EFV)

Dronabinol

Do Not Coadminister

Efavirenz (EFV)

Drospirenone (COC)

Potential Interaction

Efavirenz (EFV)

Drospirenone (HRT)

No Interaction Expected

Efavirenz (EFV)

Dulaglutide

No Interaction Expected

Efavirenz (EFV)

Duloxetine

Potential Interaction

Efavirenz (EFV)

Dutasteride

Potential Interaction

Efavirenz (EFV)

Dydrogesterone (HRT)

No Interaction Expected

Efavirenz (EFV)

Echinacea

No Interaction Expected

Efavirenz (EFV)

Ecstasy (MDMA)

No Interaction Expected

Efavirenz (EFV)

Edoxaban

No Interaction Expected

Efavirenz (EFV)

Eflornithine

Do Not Coadminister

Efavirenz (EFV)

Elbasvir/Grazoprevir

Potential Interaction

Efavirenz (EFV)

Eltrombopag

Do Not Coadminister

Efavirenz (EFV)

Elvitegravir/Cobicistat/ Emtricitabine/Tenofovir alafenamide (EVG/c/FTC/TAF)

Do Not Coadminister

Efavirenz (EFV)

Elvitegravir/Cobicistat/ Emtricitabine/Tenofovir-DF (EVG/c/FTC/TDF)

No Interaction Expected

Efavirenz (EFV)

Empagliflozin

No Interaction Expected

Efavirenz (EFV)

Emtricitabine (FTC)

No Interaction Expected

Efavirenz (EFV)

Emtricitabine/Tenofovir alafenamide (FTC/TAF, PrEP)

No Interaction Expected

Efavirenz (EFV)

Emtricitabine/Tenofovir-DF (FTC/TDF, PrEP)

No Interaction Expected

Efavirenz (EFV)

Enalapril

No Interaction Expected

Efavirenz (EFV)

Enflurane

No Interaction Expected

Efavirenz (EFV)

Enfuvirtide (T20)

No Interaction Expected

Efavirenz (EFV)

Enoxaparin

No Interaction Expected

Efavirenz (EFV)

Entecavir

No Interaction Expected

Efavirenz (EFV)

Ephedrine

Potential Interaction

Efavirenz (EFV)

Epirubicin

Potential Interaction

Efavirenz (EFV)

Eplerenone

No Interaction Expected

Efavirenz (EFV)

Epoprostenol

No Interaction Expected

Efavirenz (EFV)

Eprosartan

Do Not Coadminister

Efavirenz (EFV)

Ergometrine (Ergonovine)

Do Not Coadminister

Efavirenz (EFV)

Ergotamine

Potential Interaction

Efavirenz (EFV)

Erlotinib

No Interaction Expected

Efavirenz (EFV)

Ertapenem

Potential Interaction

Efavirenz (EFV)

Erythromycin

Potential Weak Interaction

Efavirenz (EFV)

Escitalopram

No Interaction Expected

Efavirenz (EFV)

Eslicarbazepine

No Interaction Expected

Efavirenz (EFV)

Esomeprazole

Potential Interaction

Efavirenz (EFV)

Estazolam

Potential Interaction

Efavirenz (EFV)

Estradiol

No Interaction Expected

Efavirenz (EFV)

Estramustine

No Interaction Expected

Efavirenz (EFV)

Ethambutol

Potential Interaction

Efavirenz (EFV)

Ethinylestradiol

No Interaction Expected

Efavirenz (EFV)

Ethionamide

Potential Interaction

Efavirenz (EFV)

Ethosuximide

Potential Interaction

Efavirenz (EFV)

Etidocaine

Do Not Coadminister

Efavirenz (EFV)

Etonogestrel (implant)

Do Not Coadminister

Efavirenz (EFV)

Etonogestrel (vaginal ring)

Potential Interaction

Efavirenz (EFV)

Etoposide

Do Not Coadminister

Efavirenz (EFV)

Etravirine (ETV)

No Interaction Expected

Efavirenz (EFV)

Eucalyptus globulus

Potential Interaction

Efavirenz (EFV)

Everolimus

No Interaction Expected

Efavirenz (EFV)

Evolocumab

Potential Interaction

Efavirenz (EFV)

Exemestane

No Interaction Expected

Efavirenz (EFV)

Exenatide

No Interaction Expected

Efavirenz (EFV)

Ezetimibe

No Interaction Expected

Efavirenz (EFV)

Famciclovir

No Interaction Expected

Efavirenz (EFV)

Famotidine

Potential Interaction

Efavirenz (EFV)

Felodipine

No Interaction Expected

Efavirenz (EFV)

Fenofibrate

Potential Interaction

Efavirenz (EFV)

Fentanyl

Potential Interaction

Efavirenz (EFV)

Fesoterodine

No Interaction Expected

Efavirenz (EFV)

Fexofenadine

Potential Interaction

Efavirenz (EFV)

Finasteride

No Interaction Expected

Efavirenz (EFV)

Fish oils

No Interaction Expected

Efavirenz (EFV)

Flecainide

Potential Interaction

Efavirenz (EFV)

Flibanserin

No Interaction Expected

Efavirenz (EFV)

Flucloxacillin

No Interaction Expected

Efavirenz (EFV)

Fluconazole

No Interaction Expected

Efavirenz (EFV)

Flucytosine

No Interaction Expected

Efavirenz (EFV)

Fludarabine

Potential Interaction

Efavirenz (EFV)

Fludrocortisone

Potential Interaction

Efavirenz (EFV)

Flunisolide

Potential Interaction

Efavirenz (EFV)

Flunitrazepam

No Interaction Expected

Efavirenz (EFV)

Fluocinolone

No Interaction Expected

Efavirenz (EFV)

Fluorouracil

No Interaction Expected

Efavirenz (EFV)

Fluoxetine

No Interaction Expected

Efavirenz (EFV)

Fluphenazine

Potential Interaction

Efavirenz (EFV)

Flurazepam

Potential Interaction

Efavirenz (EFV)

Fluticasone

Potential Weak Interaction

Efavirenz (EFV)

Fluvastatin

No Interaction Expected

Efavirenz (EFV)

Fluvoxamine

No Interaction Expected

Efavirenz (EFV)

Folic acid [alone]

No Interaction Expected

Efavirenz (EFV)

Folic acid [in multivitamins]

No Interaction Expected

Efavirenz (EFV)

Fondaparinux

Potential Interaction

Efavirenz (EFV)

Formestane

No Interaction Expected

Efavirenz (EFV)

Formoterol

Potential Interaction

Efavirenz (EFV)

Fosamprenavir (FPV)

No Interaction Expected

Efavirenz (EFV)

Foscarnet

No Interaction Expected

Efavirenz (EFV)

Fosinopril

No Interaction Expected

Efavirenz (EFV)

Furosemide

No Interaction Expected

Efavirenz (EFV)

Gabapentin

No Interaction Expected

Efavirenz (EFV)

Ganciclovir

Potential Interaction

Efavirenz (EFV)

Garlic

Potential Interaction

Efavirenz (EFV)

Gefitinib

No Interaction Expected

Efavirenz (EFV)

Gemcitabine

No Interaction Expected

Efavirenz (EFV)

Gemfibrozil

No Interaction Expected

Efavirenz (EFV)

Gentamicin

Do Not Coadminister

Efavirenz (EFV)

Gestodene (COC)

No Interaction Expected

Efavirenz (EFV)

GHB (Gamma-hydroxybutyrate)

No Interaction Expected

Efavirenz (EFV)

Ginger (Zingiber officinale)

Potential Interaction

Efavirenz (EFV)

Ginkgo biloba

Do Not Coadminister

Efavirenz (EFV)

Glecaprevir/Pibrentasvir

Potential Interaction

Efavirenz (EFV)

Glibenclamide (Glyburide)

Potential Interaction

Efavirenz (EFV)

Gliclazide

Potential Interaction

Efavirenz (EFV)

Glimepiride

Potential Interaction

Efavirenz (EFV)

Glipizide

No Interaction Expected

Efavirenz (EFV)

Glyceryl trinitrate (Nitroglycerin)

No Interaction Expected

Efavirenz (EFV)

Glycopyrronium bromide

No Interaction Expected

Efavirenz (EFV)

Goldenseal root (Hydrastis canadensis)

No Interaction Expected

Efavirenz (EFV)

Goserelin

Potential Interaction

Efavirenz (EFV)

Granisetron

No Interaction Expected

Efavirenz (EFV)

Grapefruit juice

Potential Interaction

Efavirenz (EFV)

Griseofulvin

Potential Interaction

Efavirenz (EFV)

Halofantrine

Potential Weak Interaction

Efavirenz (EFV)

Haloperidol

No Interaction Expected

Efavirenz (EFV)

Halothane

No Interaction Expected

Efavirenz (EFV)

Heparin

Potential Interaction

Efavirenz (EFV)

Heroin

Potential Interaction

Efavirenz (EFV)

Hops (Humulus lupulus)

No Interaction Expected

Efavirenz (EFV)

Hydralazine

No Interaction Expected

Efavirenz (EFV)

Hydrochlorothiazide

Potential Interaction

Efavirenz (EFV)

Hydrocodone

Potential Interaction

Efavirenz (EFV)

Hydrocortisone (oral)

No Interaction Expected

Efavirenz (EFV)

Hydrocortisone (topical)

Potential Interaction

Efavirenz (EFV)

Hydromorphone

No Interaction Expected

Efavirenz (EFV)

Hydroxyurea (Hydroxycarbamide)

No Interaction Expected

Efavirenz (EFV)

Hydroxyzine

No Interaction Expected

Efavirenz (EFV)

Ibalizumab-uiyk

No Interaction Expected

Efavirenz (EFV)

Ibandronic acid

Potential Interaction

Efavirenz (EFV)

Ibuprofen

Potential Interaction

Efavirenz (EFV)

Ifosfamide

Potential Interaction

Efavirenz (EFV)

Iloperidone

No Interaction Expected

Efavirenz (EFV)

Iloprost

Potential Interaction

Efavirenz (EFV)

Imatinib

No Interaction Expected

Efavirenz (EFV)

Imipenem/Cilastatin

Potential Interaction

Efavirenz (EFV)

Imipramine

Potential Weak Interaction

Efavirenz (EFV)

Indacaterol

Potential Interaction

Efavirenz (EFV)

Indapamide

Potential Interaction

Efavirenz (EFV)

Indinavir (IDV)

No Interaction Expected

Efavirenz (EFV)

Insulin

No Interaction Expected

Efavirenz (EFV)

Interferon alpha

No Interaction Expected

Efavirenz (EFV)

Interleukin 2 (Aldesleukin)

No Interaction Expected

Efavirenz (EFV)

Inula racemosa

No Interaction Expected

Efavirenz (EFV)

Iodine [in multivitamins]

No Interaction Expected

Efavirenz (EFV)

Ipratropium bromide

Potential Weak Interaction

Efavirenz (EFV)

Irbesartan

Potential Interaction

Efavirenz (EFV)

Irinotecan

No Interaction Expected

Efavirenz (EFV)

Iron supplements

No Interaction Expected

Efavirenz (EFV)

Isoflurane

No Interaction Expected

Efavirenz (EFV)

Isoniazid

Potential Weak Interaction

Efavirenz (EFV)

Isosorbide dinitrate

Potential Interaction

Efavirenz (EFV)

Isotretinoin

Potential Interaction

Efavirenz (EFV)

Itraconazole

Potential Interaction

Efavirenz (EFV)

Ivabradine

Potential Weak Interaction

Efavirenz (EFV)

Ivermectin

No Interaction Expected

Efavirenz (EFV)

Kanamycin

Potential Interaction

Efavirenz (EFV)

Ketamine

Do Not Coadminister

Efavirenz (EFV)

Ketoconazole

Potential Interaction

Efavirenz (EFV)

Labetalol

Potential Interaction

Efavirenz (EFV)

Lacidipine

Potential Interaction

Efavirenz (EFV)

Lacosamide

No Interaction Expected

Efavirenz (EFV)

Lactulose

No Interaction Expected

Efavirenz (EFV)

Lamivudine (3TC)

Potential Interaction

Efavirenz (EFV)

Lamotrigine

No Interaction Expected

Efavirenz (EFV)

Lansoprazole

Potential Interaction

Efavirenz (EFV)

Lapatinib

Potential Interaction

Efavirenz (EFV)

Ledipasvir/Sofosbuvir

No Interaction Expected

Efavirenz (EFV)

Lenalidomide

Potential Interaction

Efavirenz (EFV)

Lercanidipine

Potential Interaction

Efavirenz (EFV)

Letrozole

No Interaction Expected

Efavirenz (EFV)

Leuprorelin

No Interaction Expected

Efavirenz (EFV)

Levamisole (Ergamisol)

No Interaction Expected

Efavirenz (EFV)

Levetiracetam

No Interaction Expected

Efavirenz (EFV)

Levocetirizine

No Interaction Expected

Efavirenz (EFV)

Levodopa

No Interaction Expected

Efavirenz (EFV)

Levofloxacin

No Interaction Expected

Efavirenz (EFV)

Levomepromazine

Do Not Coadminister

Efavirenz (EFV)

Levonorgestrel (COC)

Potential Interaction

Efavirenz (EFV)

Levonorgestrel (Emergency Contraception)

Potential Interaction

Efavirenz (EFV)

Levonorgestrel (HRT)

Do Not Coadminister

Efavirenz (EFV)

Levonorgestrel (implant)

No Interaction Expected

Efavirenz (EFV)

Levonorgestrel (IUD)

Do Not Coadminister

Efavirenz (EFV)

Levonorgestrel (POP)

Potential Interaction

Efavirenz (EFV)

Levothyroxine

Potential Weak Interaction

Efavirenz (EFV)

Lidocaine (Lignocaine)

Potential Interaction

Efavirenz (EFV)

Linagliptin

No Interaction Expected

Efavirenz (EFV)

Linezolid

No Interaction Expected

Efavirenz (EFV)

Liquorice (Glycyrrhiza glabra)

No Interaction Expected

Efavirenz (EFV)

Liraglutide

No Interaction Expected

Efavirenz (EFV)

Lisinopril

No Interaction Expected

Efavirenz (EFV)

Lithium

No Interaction Expected

Efavirenz (EFV)

Loperamide

Potential Interaction

Efavirenz (EFV)

Lopinavir (LPV)

No Interaction Expected

Efavirenz (EFV)

Loratadine

No Interaction Expected

Efavirenz (EFV)

Lorazepam

No Interaction Expected

Efavirenz (EFV)

Lormetazepam

Potential Weak Interaction

Efavirenz (EFV)

Losartan

Potential Interaction

Efavirenz (EFV)

Lovastatin

Potential Interaction

Efavirenz (EFV)

LSD (Lysergic acid diethylamide)

Potential Interaction

Efavirenz (EFV)

Lumefantrine

Potential Interaction

Efavirenz (EFV)

Macitentan

No Interaction Expected

Efavirenz (EFV)

Magnesium supplements

Potential Interaction

Efavirenz (EFV)

Malabar nut tree (Justicia adhatoda, Adhatoda vasica)

No Interaction Expected

Efavirenz (EFV)

Mannitol

No Interaction Expected

Efavirenz (EFV)

Maprotiline

Potential Interaction

Efavirenz (EFV)

Maraviroc (MVC)

Potential Weak Interaction

Efavirenz (EFV)

Mebendazole

No Interaction Expected

Efavirenz (EFV)

Medroxyprogesterone (depot injection)

Potential Interaction

Efavirenz (EFV)

Medroxyprogesterone (oral)

Potential Interaction

Efavirenz (EFV)

Mefenamic acid

Potential Interaction

Efavirenz (EFV)

Mefloquine

No Interaction Expected

Efavirenz (EFV)

Megestrol acetate

No Interaction Expected

Efavirenz (EFV)

Meglumine antimoniate

No Interaction Expected

Efavirenz (EFV)

Melarsoprol

No Interaction Expected

Efavirenz (EFV)

Menthol

No Interaction Expected

Efavirenz (EFV)

Mephedrone

No Interaction Expected

Efavirenz (EFV)

Mercaptopurine

No Interaction Expected

Efavirenz (EFV)

Meropenem

No Interaction Expected

Efavirenz (EFV)

Mesalazine

No Interaction Expected

Efavirenz (EFV)

Mesna

No Interaction Expected

Efavirenz (EFV)

Metformin

Potential Interaction

Efavirenz (EFV)

Methadone

No Interaction Expected

Efavirenz (EFV)

Methamphetamine

No Interaction Expected

Efavirenz (EFV)

Methotrexate (Amethopterin)

No Interaction Expected

Efavirenz (EFV)

Methyldopa

No Interaction Expected

Efavirenz (EFV)

Methylphenidate

Potential Interaction

Efavirenz (EFV)

Methylprednisolone

No Interaction Expected

Efavirenz (EFV)

Metoclopramide

No Interaction Expected

Efavirenz (EFV)

Metolazone

No Interaction Expected

Efavirenz (EFV)

Metoprolol

No Interaction Expected

Efavirenz (EFV)

Metronidazole

No Interaction Expected

Efavirenz (EFV)

Mexiletine

Potential Weak Interaction

Efavirenz (EFV)

Mianserin

No Interaction Expected

Efavirenz (EFV)

Miconazole

Do Not Coadminister

Efavirenz (EFV)

Midazolam (oral)

Do Not Coadminister

Efavirenz (EFV)

Midazolam (parenteral)

Potential Interaction

Efavirenz (EFV)

Mifepristone

No Interaction Expected

Efavirenz (EFV)

Milk thistle

No Interaction Expected

Efavirenz (EFV)

Milnacipran

No Interaction Expected

Efavirenz (EFV)

Miltefosine

Potential Interaction

Efavirenz (EFV)

Minaxolone

No Interaction Expected

Efavirenz (EFV)

Mirabegron

Potential Interaction

Efavirenz (EFV)

Mirtazapine

No Interaction Expected

Efavirenz (EFV)

Misoprostol

Potential Interaction

Efavirenz (EFV)

Mitoxantrone

Potential Interaction

Efavirenz (EFV)

Modafinil

Potential Interaction

Efavirenz (EFV)

Mometasone

Potential Weak Interaction

Efavirenz (EFV)

Montelukast

Potential Interaction

Efavirenz (EFV)

Morphine

Potential Interaction

Efavirenz (EFV)

Moxifloxacin

No Interaction Expected

Efavirenz (EFV)

Multivitamins

Potential Interaction

Efavirenz (EFV)

Mycophenolate

No Interaction Expected

Efavirenz (EFV)

Naftidrofuryl

No Interaction Expected

Efavirenz (EFV)

Naloxone

No Interaction Expected

Efavirenz (EFV)

Naltrexone

No Interaction Expected

Efavirenz (EFV)

Nandrolone

Potential Interaction

Efavirenz (EFV)

Naproxen

Potential Interaction

Efavirenz (EFV)

Nateglinide

No Interaction Expected

Efavirenz (EFV)

Nebivolol

Potential Interaction

Efavirenz (EFV)

Nefazodone

No Interaction Expected

Efavirenz (EFV)

Neostigmine

Do Not Coadminister

Efavirenz (EFV)

Nevirapine (NVP)

Potential Interaction

Efavirenz (EFV)

Nicardipine

No Interaction Expected

Efavirenz (EFV)

Niclosamide

No Interaction Expected

Efavirenz (EFV)

Nicorandil

No Interaction Expected

Efavirenz (EFV)

Nicotinamide (Niacinamide) [in multivitamins]

Potential Interaction

Efavirenz (EFV)

Nifedipine

No Interaction Expected

Efavirenz (EFV)

Nifurtimox

Potential Interaction

Efavirenz (EFV)

Nilotinib

Potential Interaction

Efavirenz (EFV)

Nimesulide

Potential Interaction

Efavirenz (EFV)

Nisoldipine

Potential Interaction

Efavirenz (EFV)

Nitrendipine

No Interaction Expected

Efavirenz (EFV)

Nitrofurantoin

No Interaction Expected

Efavirenz (EFV)

Nitrous oxide

Do Not Coadminister

Efavirenz (EFV)

Norelgestromin (patch)

Do Not Coadminister

Efavirenz (EFV)

Norethisterone [Norethindrone] (COC)

Potential Interaction

Efavirenz (EFV)

Norethisterone [Norethindrone] (HRT)

Potential Interaction

Efavirenz (EFV)

Norethisterone [Norethindrone] (IM depot injection)

Do Not Coadminister

Efavirenz (EFV)

Norethisterone [Norethindrone] (POP)

Do Not Coadminister

Efavirenz (EFV)

Norgestimate (COC)

Do Not Coadminister

Efavirenz (EFV)

Norgestrel (COC)

Potential Interaction

Efavirenz (EFV)

Norgestrel (HRT)

No Interaction Expected

Efavirenz (EFV)

Nortriptyline

No Interaction Expected

Efavirenz (EFV)

Nystatin

No Interaction Expected

Efavirenz (EFV)

Ofloxacin

Potential Interaction

Efavirenz (EFV)

Olanzapine

No Interaction Expected

Efavirenz (EFV)

Olmesartan

No Interaction Expected

Efavirenz (EFV)

Olodaterol

Do Not Coadminister

Efavirenz (EFV)

Ombitasvir/Paritaprevir/r

Do Not Coadminister

Efavirenz (EFV)

Ombitasvir/Paritaprevir/r + Dasabuvir

No Interaction Expected

Efavirenz (EFV)

Omeprazole

No Interaction Expected

Efavirenz (EFV)

Ondansetron

Potential Weak Interaction

Efavirenz (EFV)

Orlistat

No Interaction Expected

Efavirenz (EFV)

Oseltamivir

No Interaction Expected

Efavirenz (EFV)

Oxaliplatin

No Interaction Expected

Efavirenz (EFV)

Oxamniquine

No Interaction Expected

Efavirenz (EFV)

Oxandrolone

No Interaction Expected

Efavirenz (EFV)

Oxazepam

No Interaction Expected

Efavirenz (EFV)

Oxcarbazepine

Potential Interaction

Efavirenz (EFV)

Oxprenolol

Potential Interaction

Efavirenz (EFV)

Oxybutynin

Potential Interaction

Efavirenz (EFV)

Oxycodone

No Interaction Expected

Efavirenz (EFV)

Oxytocin

Potential Interaction

Efavirenz (EFV)

Paclitaxel

Potential Weak Interaction

Efavirenz (EFV)

Paliperidone

No Interaction Expected

Efavirenz (EFV)

Pantoprazole

No Interaction Expected

Efavirenz (EFV)

Para-aminosalicylic acid

No Interaction Expected

Efavirenz (EFV)

Paracetamol (Acetaminophen)

No Interaction Expected

Efavirenz (EFV)

Paromomycin

No Interaction Expected

Efavirenz (EFV)

Paroxetine

Potential Interaction

Efavirenz (EFV)

Pazopanib

No Interaction Expected

Efavirenz (EFV)

Peginterferon alfa-2a

No Interaction Expected

Efavirenz (EFV)

Peginterferon alfa-2b

No Interaction Expected

Efavirenz (EFV)

Penicillamine

No Interaction Expected

Efavirenz (EFV)

Penicillins

No Interaction Expected

Efavirenz (EFV)

Pentamidine

No Interaction Expected

Efavirenz (EFV)

Pentoxifylline

Potential Interaction

Efavirenz (EFV)

Perazine

No Interaction Expected

Efavirenz (EFV)

Periciazine

No Interaction Expected

Efavirenz (EFV)

Perindopril

No Interaction Expected

Efavirenz (EFV)

Perphenazine

Potential Interaction

Efavirenz (EFV)

Pethidine (Meperidine)

Potential Interaction

Efavirenz (EFV)

Phencyclidine (PCP)

No Interaction Expected

Efavirenz (EFV)

Phenelzine

Potential Interaction

Efavirenz (EFV)

Phenobarbital (Phenobarbitone)

Potential Interaction

Efavirenz (EFV)

Phenprocoumon

Potential Interaction

Efavirenz (EFV)

Phenytoin

No Interaction Expected

Efavirenz (EFV)

Phytomenadione (Vitamin K) [in multivitamins]

No Interaction Expected

Efavirenz (EFV)

Pilocarpine

Do Not Coadminister

Efavirenz (EFV)

Pimozide

No Interaction Expected

Efavirenz (EFV)

Pindolol

Potential Interaction

Efavirenz (EFV)

Pioglitazone

No Interaction Expected

Efavirenz (EFV)

Piperacillin

Potential Interaction

Efavirenz (EFV)

Piperaquine

No Interaction Expected

Efavirenz (EFV)

Pipotiazine

Potential Interaction

Efavirenz (EFV)

Piroxicam

No Interaction Expected

Efavirenz (EFV)

Pitavastatin

No Interaction Expected

Efavirenz (EFV)

Poppers (Amyl nitrate)

Potent