Interaction Checker

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Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Abacavir (ABC)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Acamprosate

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Acarbose

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Acenocoumarol

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Acetazolamide

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Aciclovir (Acyclovir)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Acitretin

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Aclidinium bromide

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Adalimumab

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Adefovir

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Adrenaline (Epinephrine)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

African Potato

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Agomelatine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Albendazole

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Albuvirtide (ABT)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Alcohol

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Alcuronium

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Alendronic Acid

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Alfentanil

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Alfuzosin

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Aliskiren

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Allopurinol

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Almotriptan

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Aloe vera

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Alosetron

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Alprazolam

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Amantadine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Ambrisentan

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Amikacin

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Amiloride

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Aminophylline

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Amiodarone

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Amisulpride

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Amitriptyline

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Amlodipine

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Amodiaquine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Amoxicillin

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Amphetamine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Amphotericin B

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Ampicillin

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Anastrozole

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Anidulafungin

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Antacids

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Anti-thymocyte globulin

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Apixaban

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Apomorphine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Aprepitant

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Argatroban

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Aripiprazole

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Artemisinin

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Ascorbic Acid (Vitamin C) [in multivitamins]

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Asenapine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Asparaginase

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Aspirin (Analgesic)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Aspirin (Anti-platelet)

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Astemizole

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Atazanavir alone (ATV)

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Atazanavir/cobicistat (ATV/c)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Atazanavir + ritonavir (ATV/r)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Atenolol

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Atorvastatin

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Atovaquone

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Atropine

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Avanafil

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Azathioprine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Azithromycin

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Baclofen

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Basiliximab

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Beclometasone

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Bedaquiline

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Belatacept

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Benazepril

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Bendroflumethiazide

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Benserazide

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Benznidazole

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Bepridil

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Betahistine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Betamethasone

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Betrixaban

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Bevacizumab

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Bexarotene

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Bezafibrate

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Bictegravir/ Emtricitabine/Tenofovir alafenamide (BIC/FTC/TAF)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Biperiden

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Bisacodyl

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Bisoprolol

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Black cohosh (Actaea racemosa, Cimicifuga racemosa)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Bleomycin

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Bortezomib

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Bosentan

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Bromazepam

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Budesonide

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Bupivacaine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Buprenorphine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Bupropion (Amfebutamone)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Buspirone

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Caffeine citrate

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Calcium folinate

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Calcium supplements

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Canagliflozin

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Candesartan

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Cannabidiol (CBD)

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Cannabis

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Capecitabine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Capreomycin

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Captopril

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Carbamazepine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Carbidopa

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Carbimazole

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Carboplatin

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Carvedilol

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Caspofungin

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Cat's Claw (Uncaria tomentosa)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Cefalexin

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Cefazolin

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Cefixime

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Cefotaxime

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Ceftazidime

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Ceftriaxone

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Celecoxib

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Cetirizine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Cetuximab

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Chlorambucil

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Chloramphenicol

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Chlordiazepoxide

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Chloroquine

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Chlorphenamine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Chlorpromazine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Chlortalidone

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Ciclesonide

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Ciclosporin (Cyclosporine)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Cidofovir

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Cilazapril

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Cimetidine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Ciprofloxacin

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Cisapride

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Cisatracurium

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Cisplatin

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Citalopram

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Clarithromycin

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Clavulanic acid

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Clindamycin

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Clobazam

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Clobetasol

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Clofazimine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Clofibrate

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Clomifene

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Clomipramine (Chlorimipramine)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Clonazepam

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Clonidine

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Clopidogrel

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Clorazepate

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Cloxacillin

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Clozapine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Cocaine

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Codeine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Colchicine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Colecalciferol (Vitamin D3) [in multivitamins]

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Cubeb pepper (Piper cubeba)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Cyanocobalamin (Vitamin B12) [in multivitamins]

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Cyclophosphamide

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Cycloserine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Cyproterone acetate

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Cytarabine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Dabigatran

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Dacarbazine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Daclatasvir

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Dactinomycin

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Dalteparin

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Dapagliflozin

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Dapsone

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Darifenacin

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Darunavir/cobicistat (DRV/c)

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Darunavir/Cobicistat/ Emtricitabine/Tenofovir alafenamide (DRV/c/FTC/TAF)

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Darunavir + ritonavir (DRV/r)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Dasatinib

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Daunorubicin

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Delamanid

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Denosumab

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Desflurane

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Desipramine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Desogestrel (COC)

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Desogestrel (POP)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Dexamethasone

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Dexmedetomidine

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Dextropropoxyphene

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Diamorphine (diacetylmorphine)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Diazepam

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Diclofenac

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Didanosine (ddI)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Diethylcarbamazine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Digoxin

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Dihydrocodeine

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Dihydroergotamine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Diloxanide

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Diltiazem

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Diphenhydramine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Dipyridamole

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Disopyramide

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Disulfiram

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Docetaxel

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Dofetilide

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Dolasetron

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Dolutegravir (DTG)

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Dolutegravir/Abacavir/ Lamivudine (DTG/ABC/3TC)

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Dolutegravir/Lamivudine (DTG/3TC)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Dolutegravir/Rilpivirine (DTG/RPV)

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Domperidone

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Dopamine

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Doravirine (DOR)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Doravirine/Lamivudine/ Tenofovir-DF (DOR/3TC/TDF)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Doxazosin

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Doxepin

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Doxorubicin

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Doxycycline

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Droloxifene

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Dronabinol

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Drospirenone (COC)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Drospirenone (HRT)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Dulaglutide

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Duloxetine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Dutasteride

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Dydrogesterone (HRT)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Echinacea

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Ecstasy (MDMA)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Edoxaban

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Efavirenz (EFV)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Eflornithine

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Elbasvir/Grazoprevir

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Eltrombopag

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Elvitegravir/Cobicistat/ Emtricitabine/Tenofovir alafenamide (EVG/c/FTC/TAF)

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Elvitegravir/Cobicistat/ Emtricitabine/Tenofovir-DF (EVG/c/FTC/TDF)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Empagliflozin

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Emtricitabine (FTC)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Emtricitabine/Tenofovir alafenamide (FTC/TAF, PrEP)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Emtricitabine/Tenofovir-DF (FTC/TDF, PrEP)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Enalapril

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Enflurane

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Enoxaparin

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Entecavir

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Ephedrine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Epirubicin

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Eplerenone

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Epoprostenol

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Eprosartan

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Ergometrine (Ergonovine)

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Ergotamine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Erlotinib

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Ertapenem

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Erythromycin

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Escitalopram

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Eslicarbazepine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Esomeprazole

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Estazolam

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Estradiol

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Estramustine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Ethambutol

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Ethinylestradiol

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Ethionamide

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Ethosuximide

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Etidocaine

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Etonogestrel (implant)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Etonogestrel (vaginal ring)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Etoposide

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Etravirine (ETR)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Eucalyptus globulus

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Everolimus

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Evolocumab

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Exemestane

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Exenatide

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Ezetimibe

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Famciclovir

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Famotidine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Felodipine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Fenofibrate

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Fentanyl

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Fesoterodine

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Fexofenadine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Finasteride

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Fish oils

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Flecainide

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Flibanserin

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Flucloxacillin

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Fluconazole

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Flucytosine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Fludarabine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Fludrocortisone

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Flunisolide

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Flunitrazepam

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Fluocinolone

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Fluorouracil

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Fluoxetine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Fluphenazine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Flurazepam

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Fluticasone

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Fluvastatin

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Fluvoxamine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Folic acid [alone]

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Folic acid [in multivitamins]

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Fondaparinux

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Formestane

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Formoterol

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Fosamprenavir (FPV)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Foscarnet

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Fosinopril

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Furosemide

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Gabapentin

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Ganciclovir

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Garlic

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Gefitinib

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Gemcitabine

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Gemfibrozil

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Gentamicin

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Gestodene (COC)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

GHB (Gamma-hydroxybutyrate)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Ginger (Zingiber officinale)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Ginkgo biloba

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Glecaprevir/Pibrentasvir

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Glibenclamide (Glyburide)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Gliclazide

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Glimepiride

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Glipizide

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Glyceryl trinitrate (Nitroglycerin)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Glycopyrronium bromide

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Goldenseal root (Hydrastis canadensis)

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Goserelin

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Granisetron

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Grapefruit juice

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Griseofulvin

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Halofantrine

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Haloperidol

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Halothane

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Heparin

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Heroin

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Hops (Humulus lupulus)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Hydralazine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Hydrochlorothiazide

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Hydrocodone

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Hydrocortisone (oral)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Hydrocortisone (topical)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Hydromorphone

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Hydroxyurea (Hydroxycarbamide)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Hydroxyzine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Ibalizumab-uiyk (IBA)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Ibandronic acid

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Ibuprofen

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Ifosfamide

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Iloperidone

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Iloprost

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Imatinib

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Imipenem/Cilastatin

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Imipramine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Indacaterol

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Indapamide

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Indinavir (IDV)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Insulin

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Interferon alpha

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Interleukin 2 (Aldesleukin)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Inula racemosa

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Iodine [in multivitamins]

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Ipratropium bromide

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Irbesartan

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Irinotecan

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Iron supplements (oral)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Isoflurane

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Isoniazid

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Isosorbide dinitrate

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Isotretinoin

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Itraconazole

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Ivabradine

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Ivermectin

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Kanamycin

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Ketamine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Ketoconazole

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Labetalol

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Lacidipine

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Lacosamide

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Lactulose

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Lamivudine (3TC)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Lamotrigine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Lansoprazole

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Lapatinib

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Ledipasvir/Sofosbuvir

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Lenalidomide

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Lercanidipine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Letrozole

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Leuprorelin

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Levamisole (Ergamisol)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Levetiracetam

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Levocetirizine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Levodopa

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Levofloxacin

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Levomepromazine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Levonorgestrel (COC)

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Levonorgestrel (Emergency Contraception)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Levonorgestrel (HRT)

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Levonorgestrel (implant)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Levonorgestrel (IUD)

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Levonorgestrel (POP)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Levothyroxine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Lidocaine (Lignocaine)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Linagliptin

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Linezolid

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Liquorice (Glycyrrhiza glabra)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Liraglutide

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Lisinopril

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Lithium

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Loperamide

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Loratadine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Lorazepam

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Lormetazepam

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Losartan

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Lovastatin

Potential Interaction

Lopinavir/ritonavir (LPV/r)

LSD (Lysergic acid diethylamide)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Lumefantrine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Macitentan

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Magnesium supplements

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Malabar nut tree (Justicia adhatoda, Adhatoda vasica)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Mannitol

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Maprotiline

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Maraviroc (MVC)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Mebendazole

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Medroxyprogesterone (depot injection)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Medroxyprogesterone (HRT)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Mefenamic acid

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Mefloquine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Megestrol acetate

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Meglumine antimoniate

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Melarsoprol

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Menthol

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Mephedrone

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Mercaptopurine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Meropenem

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Mesalazine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Mesna

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Metformin

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Methadone

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Methamphetamine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Methotrexate (Amethopterin)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Methyldopa

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Methylphenidate

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Methylprednisolone

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Metoclopramide

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Metolazone

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Metoprolol

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Metronidazole

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Mexiletine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Mianserin

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Miconazole

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Midazolam (oral)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Midazolam (parenteral)

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Mifepristone

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Milk thistle (Silybum marianum, silymarin)

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Milnacipran

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Miltefosine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Minaxolone

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Mirabegron

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Mirtazapine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Misoprostol

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Mitoxantrone

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Modafinil

Do Not Coadminister

Lopinavir/ritonavir (LPV/r)

Mometasone

Potential Weak Interaction

Lopinavir/ritonavir (LPV/r)

Montelukast

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Morphine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Moxifloxacin

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Multivitamins

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Mycophenolate

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Naftidrofuryl

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Naloxone

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Naltrexone

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Nandrolone

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Naproxen

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Nateglinide

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Nebivolol

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Nefazodone

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Neostigmine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Nevirapine (NVP)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Nicardipine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Niclosamide

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Nicorandil

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Nicotinamide (Niacinamide) [in multivitamins]

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Nifedipine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Nifurtimox

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Nilotinib

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Nimesulide

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Nisoldipine

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Nitrendipine

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Nitrofurantoin

No Interaction Expected

Lopinavir/ritonavir (LPV/r)

Nitrous oxide

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Norelgestromin (patch)

Potential Interaction

Lopinavir/ritonavir (LPV/r)

Norethisterone [Norethindrone] (COC)