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No Interaction Expected

Zidovudine (AZT, ZDV)

Morphine

Quality of Evidence: Very Low

Summary:

Coadministration has not been studied but based on metabolism and clearance, a clinically relevant drug interaction is unlikely. Morphine is mainly glucuronidated to morphine-3-glucuronide (UGT2B7>UGT1A1) and, to a lesser extent, to the pharmacologically active morphine-6-glucuronide (UGT2B7>UGT1A1). Zidovudine does not affect this metabolic pathway.

Description:

(See Summary)

View all available interactions with Zidovudine (AZT, ZDV) by clicking here.

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