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Do Not Coadminister

Nevirapine (NVP)

Rilpivirine (RPV)

Quality of Evidence: Very Low

Summary:

Coadministration is not recommended as it may decrease rilpivirine concentrations. Combining two NNRTIs has not been shown to be beneficial.

Description:

This interaction has not been studied. The concomitant administration of nevirapine with NNRTIs is not recommended.
Viramune Summary of Product Characteristics, Boehringer Ingelheim Ltd, November 2019.

Plasma concentrations may be altered. Nevirapine should not be coadministered with another NNRTI as this combination has not been shown to be beneficial.
Viramune Prescribing Information, Boehringer Ingelheim Pharmaceuticals Inc, October 2019.

Coadministration with nevirapine has not been studied. It is not recommended to co-administer rilpivirine with other NNRTIs.
Edurant Summary of Product Characteristics, Janssen-Cilag Ltd, January 2019.

Coadministration may decrease rilpivirine concentrations. It is not recommended to co-administer rilpivirine with other NNRTIs.
Edurant US Prescribing Information, Janssen Therapeutics, May 2019.

View all available interactions with Nevirapine (NVP) by clicking here.

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