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Do Not Coadminister

Rilpivirine/ Emtricitabine/Tenofovir alafenamide (RPV/FTC/TAF)

Tenofovir-DF (TDF)

Quality of Evidence: Very Low

Summary:

Odefsey (rilpivirine, emtricitabine, tenofovir alafenamide) is indicated for use as a complete regimen for the treatment of HIV-1 infection and should not be administered with other antiretroviral products. In addition, tenofovir-DF should not be coadministered with products containing tenofovir alafenamide.

Description:

Odefsey is indicated for use as a complete regimen for the treatment of HIV-1 infection and should not be co-administered with other antiretroviral medicinal products. Odefsey should not be co-administered with medicinal products containing tenofovir disoproxil.
Odefsey Summary of Product Characteristics, Gilead Sciences Ltd, January 2019.

Because Odefsey is a complete regimen, coadministration with other antiretroviral medications for the treatment of HIV-1 infection is not recommended.
Odefsey US Prescribing Information, Gilead Sciences Inc, October 2018.

Viread should not be administered concomitantly with other medicinal products containing tenofovir disoproxil fumarate or tenofovir alafenamide.
Viread Summary of Product Characteristics, Gilead Sciences Ltd, September 2016.

View all available interactions with Rilpivirine/ Emtricitabine/Tenofovir alafenamide (RPV/FTC/TAF) by clicking here.

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