Interaction Checker

Apps

Download from the AppStore

Download from Google Play

Interaction Checker
About Us
Mission Statement Meet the Team Steering Committee
Interaction Checkers
Interaction Checker Español Checker Français Checker Português Checker Interaction Checker Lite View All Checker
Prescribing Resources Videos Site News
Contact Us
Feedback Form Suggest a Drug
Support Us
Cookies help us deliver our services. By using our services, you agree to our use of cookies. Learn more

No Interaction Expected

Zidovudine (AZT, ZDV)

Darunavir/cobicistat (DRV/c)

Quality of Evidence: Very Low

Summary:

Coadministration has not been studied but based on metabolism and clearance a clinically significant interaction is unlikely as zidovudine is primarily renally excreted.

Description:

Based on the different elimination pathways of the other NRTIs (i.e. zidovudine) that are primarily renally excreted, no interactions are expected for this medicinal compound and darunavir/cobicistat. Darunavir/cobicistat can be used with this NRTI without dose adjustment.
Rezolsta Summary of Product Characteristics, Janssen-Cilag Ltd, July 2023.

Clinically relevant drug-drug interactions are not anticipated with concomitant use of darunavir and cobicistat with zidovudine.
Prezcobix US Prescribing Information, Janssen Pharmaceuticals Inc, March 2023.

View all available interactions with Zidovudine (AZT, ZDV) by clicking here.

SPONSORS
EDITORIAL SPONSORS
Awards and commendations
bma-foundation-for-medical-research british-medical-journal-2018 queens_aniversary_prize_2017 rcp-excellence-patient-care-awards-2017
healthline-best-HIV-and-AIDS-apps-of-2019
building_better_healthcare_awards_2016 healthline-best-HIV-and-AIDS-apps-of-2016
Cookie Policy Privacy Statement Terms & Conditions

Copyright © 2025 The University of Liverpool. All rights reserved.