No Interaction Expected
Emtricitabine/Tenofovir-DF (FTC/TDF, PrEP)
Quality of Evidence:
Coadministration has not been studied but based on metabolism and clearance a clinically significant interaction. Penicillins are mainly eliminated in the urine (20% by glomerular filtration and 80% by tubular secretion via OAT). Concentrations of tenofovir and penicillins (but not emtricitabine) could be possibly increased due to competition for active tubular secretion, however, no a priori dosage adjustment is recommended.
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Emtricitabine/Tenofovir-DF (FTC/TDF, PrEP) by clicking