No Interaction Expected
Emtricitabine/Tenofovir-DF (FTC/TDF, PrEP)
Quality of Evidence:
Coadministration has not been studied but based on metabolism and clearance a clinically significant interaction is unlikely. Chlorphenamine is predominantly metabolized via CYP2D6 and approximately 22% of a chlorphenamine dose is excreted unchanged in the urine. There is little potential for an interaction with emtricitabine and tenofovir via competition for renal elimination pathways.
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Emtricitabine/Tenofovir-DF (FTC/TDF, PrEP) by clicking