No Interaction Expected
Emtricitabine/Tenofovir-DF (FTC/TDF, PrEP)
Quality of Evidence:
Coadministration has not been studied but based on metabolism and clearance a clinically significant interaction is unlikely. Bisoprolol is partly metabolized by CYP3A4 and CYP2D6 and partly eliminated unchanged in the urine. In vitro data indicate that bisoprolol inhibits OCT2, however a clinically relevant interaction with emtricitabine or tenofovir is unlikely as these drugs are eliminated by different renal transporters.
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Emtricitabine/Tenofovir-DF (FTC/TDF, PrEP) by clicking