No Interaction Expected
Emtricitabine/Tenofovir-DF (FTC/TDF, PrEP)
Quality of Evidence:
Coadministration has not been studied. Garlic supplements have been shown to decrease unboosted saquinavir AUC by 50% in a clinical trial likely due to induction of intestinal CYP3A4 and/or P-gp by garlic. No effect on emtricitabine is expected. Based on the drug interaction study with rifampicin (another inducer of P-gp), no significant effect is expected on tenofovir-DF.
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Emtricitabine/Tenofovir-DF (FTC/TDF, PrEP) by clicking