No Interaction Expected
Emtricitabine/Tenofovir-DF (FTC/TDF, PrEP)
Phytomenadione (Vitamin K) [in multivitamins]
Quality of Evidence:
Coadministration has not been studied but based on metabolism and clearance a clinically significant interaction is unlikely with phytomenadione when given alone or in multivitamins. Metabolism of phytomenadione is thought to involve CYP4F2 and glucuronidation. Renal elimination of phytomenadione is minimal, therefore, there is little potential for an interaction with emtricitabine and tenofovir-DF due to competition for renal elimination pathways.
View all available interactions with
Emtricitabine/Tenofovir-DF (FTC/TDF, PrEP) by clicking