No Interaction Expected
Emtricitabine/Tenofovir-DF (FTC/TDF, PrEP)
Quality of Evidence:
Coadministration has not been studied but based on metabolism and clearance a clinically significant interaction is unlikely. Amantadine is mainly eliminated in the kidney by glomerular filtration and active secretion via OCT2. Emtricitabine and tenofovir are unlikely to interfere with amantadine renal elimination as they are eliminated by different renal transporters.
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Emtricitabine/Tenofovir-DF (FTC/TDF, PrEP) by clicking