No Interaction Expected
Emtricitabine/Tenofovir-DF (FTC/TDF, PrEP)
Quality of Evidence: Very Low
Based on metabolism and clearance a clinically significant interaction with emtricitabine/tenofovir-DF is unlikely. Nevirapine plasma concentrations when administered with emtricitabine/tenofovir-DF (n=7) were similar to historical values. Tenofovir and nevirapine plasma levels remain unchanged when tenofovir-DF and nevirapine were co-administered. Emtricitabine/tenofovir-DF and nevirapine can be co-administered without dose adjustments.