Quality of Evidence:
Coadministration has not been studied. Tinidazole is partly metabolized by CYP3A4 and lopinavir may increase tinidazole concentrations, although to a limited extent. No a priori dose adjustment is warranted with lopinavir/ritonavir tablets. However, coadministration with lopinavir/ritonavir oral suspension is not recommended as it contains alcohol and may lead to a disulfiram-like reaction.
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Lopinavir/ritonavir (LPV/r) by clicking