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Potential Interaction

Efavirenz (EFV)

Sildenafil (Pulmonary Arterial Hypertension)

Quality of Evidence: Very Low

Summary:

Coadministration with CYP3A4 inducers, such as efavirenz, may decrease sildenafil concentrations. The efficacy of sildenafil should be closely monitored and dose adjustments may be required.

Description:

Efficacy of sildenafil should be closely monitored in patients using concomitant potent CYP3A4 inducers. Dose adjustments of sildenafil may be required when co-administered with CYP3A4 inducers.
Revatio (sildenafil) Summary of Product Characteristics, Pfizer Ltd, December 2009

View all available interactions with Efavirenz (EFV) by clicking here.

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