No Interaction Expected
Quality of Evidence:
Coadministration has not been studied but based on metabolism and clearance a clinically relevant drug interaction is unlikely. Ofloxacin is primarily eliminated by the kidney. In vitro data suggest that ofloxacin weakly inhibits the renal transporter OAT3. A clinically relevant drug-drug interaction is unlikely as tenofovir is primarily excreted via OAT1.
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Tenofovir-DF (TDF) by clicking