No Interaction Expected
Quality of Evidence:
Coadministration has not been studied but based on metabolism and clearance a clinically significant interaction is unlikely as levofloxacin is metabolised to a very small extent. Levofloxacin is eliminated renally mainly by glomerular filtration and active secretion (possibly OCT2) whereas tenofovir is eliminated by different renal transporters.
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Tenofovir-DF (TDF) by clicking